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. 2001 Feb 1;29(3):e12. doi: 10.1093/nar/29.3.e12

Figure 5.

Figure 5

The level of 8-OH-dGuo measured by LC/IDMS-SIM and the level of 8-OH-Gua measured by GC/IDMS-SIM in DNA under various conditions. Columns 1–3: in calf thymus DNA, measured by LC/IDMS-SIM with hydrolysis by four enzymes, GC/IDMS-SIM with hydrolysis by formic acid and by GC/IDMS-SIM with hydrolysis by Fpg protein, respectively (this work). Columns 4 and 5: in calf thymus DNA, previously measured by GC/IDMS-SIM with hydrolysis by formic acid and by GC/IDMS-SIM with hydrolysis by Fpg protein, respectively (16). Columns 6–8: in DNA isolated from cultured HeLa cells, measured by LC/IDMS-SIM with hydrolysis by four enzymes, GC/IDMS-SIM with hydrolysis by formic acid and by GC/IDMS-SIM with hydrolysis by Fpg protein, respectively (this work). All values in columns 1–8 represent the average (± standard deviation) of three to six independent measurements. Columns 9 and 10: in calf thymus DNA measured by LC/MS/MS (9,15). Column 11: in rat liver measured by LC/MS/MS (8). No standard deviation or standard error was given for the values in columns 9–11.