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Radiation dose–yield plots of 8-OH-dGuo and 8-OH-Gua in DNA exposed to various doses of ionizing radiation. Circle, 8-OH-dGuo measured by LC/IDMS-SIM with hydrolysis by four enzymes. Square, 8-OH-Gua measured by GC/IDMS-SIM with hydrolysis by formic acid. All values represent the average (± standard deviation) of three independent measurements.
