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. 2010 Dec 16;18(1):31–38. doi: 10.1093/dnares/dsq029

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© The Author 2010. Published by Oxford University Press on behalf of Kazusa DNA Research Institute

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Sequence coverage across on-target and off-target regions. Sequence coverage is plotted for the single non-indexed and indexed samples at an on-target site (PTBP2 on chromosome 1; A) and at an off-target site (chromosome 12; B). Inclusion of the index does not dramatically change the pattern of sequence coverage at on-target or off-target regions. The higher sequence coverage observed for the non-indexed sample compared with the indexed sample reflects the larger number of clusters that passed QC filtering during the sequence run (Supplementary Table SB).