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Mean changes in lean mass from baseline to years 1, 3, and 6. P values (2-sided t test) indicate the difference between the intervention and comparison groups at years 1, 3, and 6. With the use of generalized estimating equation models, interaction between the intervention and visit year was tested. We found that the association between the intervention and change in lean mass did not significantly vary over time, P = 0.92 (Wald test).
