TABLE 5.
Overall changes in lean mass in women in the intervention group compared with the comparison group, stratified by baseline characteristics1
| Baseline characteristics | Difference in lean mass (95% CI)2 | P value | P for interaction |
| g | |||
| Age | 0.88 | ||
| 50–54 y | −118.79 (−397.65, 160.07) | 0.40 | |
| 55–59 y | −236.63 (−474.05, 0.78) | 0.05 | |
| 60–64 y | −28.64 (−259.25, 201.97) | 0.81 | |
| 65–69 y | −331.01 (−548.20, −113.82) | 0.003 | |
| 70–79 y | −112.65 (−348.58, 123.27) | 0.35 | |
| Race-ethnicity | 0.11 | ||
| Blacks | 94.44 (−211.24, 400.11) | 0.55 | |
| Hispanics | 8.88 (−491.13, 508.88) | 0.97 | |
| Whites | −230.11 (−346.32, −113.91) | <0.001 | |
| Treated diabetes | 0.62 | ||
| No | −149.02 (−257.31, −40.73) | 0.007 | |
| Yes | −289.22 (−829.77, 251.32) | 0.29 | |
| BMI3 | 0.089 | ||
| Normal | 27.45 (−130.22, 185.12) | 0.73 | |
| Overweight | −282.43 (−442.30, −122.57) | 0.001 | |
| Obesity class I | −165.09 (−413.29, 83.12) | 0.19 | |
| Obesity class II | −305.86 (−752.33, 140.61) | 0.18 | |
| Obesity class III | 0.74 (−712.22, 713.70) | 0.998 | |
| HT use | 0.049 | ||
| No | −271.63 (−423.77, −119.49) | <0.001 | |
| Yes | −55.32 (−207.76, 97.13) | 0.48 | |
| HT use (HT trial only) | <0.001 | ||
| No | −1059.64 (−1465.72, −653.56) | <0.001 | |
| Yes | 365.78 (−48.63, 780.18) | 0.08 |
1
HT, hormone therapy.
2
β Values (and 95% CIs) from generalized estimating equation models reflect the mean change in lean mass from baseline in the intervention group compared with the comparison group during follow-up, stratified by the above baseline characteristics.
3
The small numbers of underweight women were combined with normal-weight women for these analyses.