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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Osteoarthritis Cartilage. 2010 Nov 26;19(2):171–179. doi: 10.1016/j.joca.2010.11.009

Table 3.

Univariate and multivariate mixed effects regression of glycosaminoglycan content as a percenter of wet weight (sGAG) with T2 relaxation time and age for the normal T2 relaxation time subset. Normal T2 relaxation time is defined to be T2 relaxation time less than the mean plus one standard deviation of the T2 relaxation time for all samples. The regression coefficients are given; the p-value for each regression coefficient is given in the footnote. Regression R2 was calculated by squaring the linear correlation between model predictions and observed values.

Table 3. Regression Coefficients on sGAG for Normal T2 Specimens
Samples (N) Threshold T2
value (ms)
Univariate sGAG analysis Multivariate sGAG analysis
Age R2 T2 R2 Age T2 R2
Bottom region (69) 36 −0.03*** 0.57 −0.03^ - −0.03** −0.03^ 0.58
Top region (73) 43 −0.03*** 0.67 −0.03# - −0.03** −0.02# 0.68
Full thickness (67) 38 −0.03*** 0.69 −0.02^ - −0.03*** −0.02^ 0.70
Top & Bottom (142) -- −0.03*** 0.41 −0.08*** 0.58 −0.03** −0.08*** 0.58
**

p<0.01

***

p<0.001

#

p>0.10

^

p>0.20