Table 1.
Placentas from sheep and goats with naturally occurring scrapie: dam and fetal PRNP genotypes, disease status of dam
| Dam | Progeny | ||||
|
Placenta IDa |
Animal ID |
PRNPb |
Parturition to death (days) |
Year born/ No. progeny |
PRNP |
| G569 | 1/3684C | wt/wt | 96 | 2006/1 | wt/240P |
| G736A | 2/3953N | 240P/240P | 332 | 2008/1 | 240P/240P |
| G736Z | 2/3953N | 240P/240P | 332 | 2008/1 | 240P/146S240P |
| G742 | 2/3950M | wt/240P | 431 | 2008/1 | wt/240P |
| G797 | 2/3950M | wt/240P | 83 | 2009/3 | wt/240P |
| G836 | 2/3987S | 240P/240P | 181 | 2009/1 | 240P/240P |
| S345 | 2924 | ARQ/ARQ | 205 | 2005/3 | ARQ/ARQ |
| S630 | 3345 | ARQ/ARQ | 249 | 2007/2 | ARQ/ARQ |
| S738 | 3602 | ARQ/ARQ | 378 | 2008/2 | ARQ/ARQ |
| S811 | 3602 | ARQ/ARQ | 22 | 2009/3 | ARQ/ARQ |
| S758 | 3768 | ARQ/ARQ | 523 | 2008/1 | ARQ/ARQ |
| S796 | 3768 | ARQ/ARQ | 181 | 2009/1 | ARQ/ARQ |
| S850 | 4161 | ARQ/ARQ | 358 | 2009/2 | ARQ/ARQ |
a Shed cotyledons from goats (G) or sheep (S)
b PRNP genotypes included the wild type (wt) allele on a 240 S backbone with no other mutations, an allele differing only at codon 240 (240P) or an allele on the 240P backbone with a second polymorphism at codon 146 (S substituted for N) (146S240P)