Table 2.
Effects of S-DEP and minocycline on gene expression in brain tissues
| Target Gene | Main Effect, S-DEP (df = 1,28) | Main Effect, Minocycline (df = 1,28) | Interaction (df = 1,28) |
|---|---|---|---|
| c-fos | F = 123.0, P < 0.001 | NS | F = 6.0, P = 0.021 |
| cd11b | F = 4.9, P = 0.035 | NS | NS |
| il-1β | NS | F = 5.9, P = 0.022 | NS |
| il-6 | NS | F = 4.8, P = 0.037 | NS |
| pbr | F = 7.4, P = 0.011* | NS | NS |
| tnfα | NS | F = 4.1, P = 0.053 | NS |
df = 1,27 for pbr