Table 4.
The mean ± standard deviation of DAT binding potentials in total striatum and in subregions of the striatum from dopaminergic-naïve RLS and Control subjects during day and night assessments
| ST | aPU | pPU | aCN | pCN | VS | |
|---|---|---|---|---|---|---|
| Control–Day (N = 20) | 1.83 ± 0.21 | 1.83 ± 0.21 | 1.84 ± 0.16 | 1.65 ± 0.18 | 1.06 ± 0.21 | 1.13 ± 0.28 |
| RLS-Day (N = 10) | 1.66 ± 0.25 | 1.66 ± 0.25 | 1.66 ± 0.23 | 1.47 ± 0.25 | 1.00 ± 0.30 | 1.00 ± 0.29 |
| Control-Night (N = 14) | 1.80 ± 0.17 | 1.80 ± 0.17 | 1.87 ± 0.15 | 1.66 ± 0.21 | 1.16 ± 0.17 | 1.12 ± 0.25 |
| RLS-Night (N = 6) | 1.55 ± 0.16 | 1.55 ± 0.16 | 1.53 ± 0.20 | 1.36 ± 0.19 | 0.85 ± 0.22 | 0.97 ± 0.22 |
| All Control vs All RLS | F = 23.1 | F = 10.8 | F = 23.3 | F = 14.1 | F = 6.73 | F = 3.0 |
| P < 0.0001 | P = 0.0019 | P < 0.0001 | P = 0.0005 | P = 0.013 | P = 0.09 | |
| Day vs Night | F = 1.6 | F = 1.2 | F = 0.82 | F = 0.61 | F = 0.18 | F = 0.07 |
| P = 0.69 | P = 0.3 | P = 0.4 | P = 0.4 | P = 0.7 | P = 0.8 | |
| Interaction | F = 0.43 | F = 0.4 | F = 2.1 | F = 1.07 | F = 3.3 | F = 0.03 |
| P = 0.52 | P = 0.6 | P = 0.2 | P = 0.3 | P = 0.08 | P = 0.9 | |
ST, total striatum; aPU, anterior putamen; pPu, posterior putamen; aCN, anterior caudate nucleus; pCN, posterior caudate nucleus; VS, ventral striatum.