Table 1. Structural analysis of the PCNA intermonomer interfaces and overall amino acid compositions.
| Homolog | Number of backbone-backboneHydrogen Bonds1 | Number ofBackbone-side chainHydrogen Bonds1 | Number ofSalt Bridges1 | ASA (Å2) 1 | Percentage of charged residues (DEKRH) | Percentage of Polar Uncharged residues (GSTNQYC) | Percentage of Hydrophobic residues (LMIVWPAF) |
| hPCNA | 8 | 4 | 1 | 709 | 26 | 32 | 42 |
| scPCNA | 8 | 1 | 1 | 654 | 29 | 28 | 44 |
| pfPCNA | 5 | 9 | 6 | 718 | 33 | 22 | 45 |
1
The analysis was carried out using the PDBePISA tool for exploration of macromolecular interfaces. The PDB entries used were 1PLQ for scPCNA, 1VYM for hPCNA and 1GE8 for pfPCNA.