Table 1.
Growth of UV-induced B cell tumors in immune-deficient but not wild type mice
| Recipient Mice* | Number of mice | Number with tumor | p‡ |
|---|---|---|---|
| Rag2-/- | 15 | 15 | _ |
| C57Bl/6 | 15 | 1 | 0.0001 |
| UV-irradiated C57Bl/6† | 15 | 2 | 0.0001 |
* 2 × 106 tumor cells were injected into the subcutaneous space of the recipient mice. Tumor growth was monitored daily. Mice were sacrificed when the tumor volume exceeded 1 cm2.
† 10 kJ/m2 UVB radiation, 3x per week for 12 weeks prior to tumor transplantation
‡ p values determined by Fisher's exact test comparing tumor growth in immune deficient Rag2-/- vs. growth in wild type or UV-irradiated wild type mice.