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. Author manuscript; available in PMC: 2012 Feb 24.
Published in final edited form as: J Med Chem. 2011 Jan 19;54(4):1059–1070. doi: 10.1021/jm101432z

Table 4.

Product formation from the decomposition of 1-3 in the presence of thiols under basic conditions.

Entry Compound Thiol
(2.5 equiv.)		 4:5 4:5
(with Cyclopentanone 10 equiv.)
1 1 GSH 2:98 12:88
2 1 TP 21:79 21:79
3 1 NAC 10:90 10:90
4 2 GSH 9:91 9:91
5 2 TP 14:86 11:89
6 2 NAC 2:98 6:94
7 3 GSH 97:3