Table 3.

Adverse effects and referrals by study group^*

	Misoprostol n = 533	Placebo n = 583	P-value**
Adverse effects reported
Nausea	8 (1.5)	8 (1.4)	0.527
Vomiting	3 (0.6)	3 (0.5)	0.614
Diarrhoea	1 (0.2)	0 (0.0)	0.478
Shivering	50 (9.4)	23 (3.9)	<0.0001
Chills/cold	53 (9.9)	29 (5.0)	<0.0001
Fever	4 (0.8)	7 (1.2)	0.326
Headache	6 (1.1)	7 (1.2)	0.566
Weakness/fatigue	9 (1.7)	8 (1.4)	0.425
Dizziness/fainting	9 (1.7)	6 (1.0)	0.244
Referrals
Woman referred for higher level of care
Multiple reasons possible	9 (1.7)	10 (1.7)	0.579
Due to PPH	2 (0.4)	3 (0.5)	0.542
Due to retained placenta	7 (1.3)	7 (1.3)	0.538
Maternal death	0 (0.0)	0 (0.0)	–

^*Numbers are n (%) unless otherwise specified.

^**One-tailed P-values are specified.