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. 2010 Aug 6;3(2):287–293. doi: 10.1159/000318873

Table 2.

Overview of studies investigating imatinib as treatment of desmoid tumors


Study No. of patients Dose of imatinib Result

Chugh et al. ASCO 2006 [12] 51 2 × 300 mg daily 36 patients had either CR, PR, (at 2 month) or SD (at 4 month)
Fayette et al. ASCO 2007 [13] 40 400 mg daily, (increased to 800 mg daily if progression) for one year after 3 month: 1 CR, 3 PR, 31 SD, 13 PD
after 13.8 month: 13 PD, 1 patient died

Response evaluation according to Response Evaluation Criteria in Solid Tumours (RECIST): CR = complete response; PR = partial response; SD = stable disease; MR = minor response; NR = not reported.