Table 1.
| Controls | PD+ICB | PD-ICB | t value except * and ** |
p-value | |
|---|---|---|---|---|---|
| Participants (no.) | 24 | 28 | 24 | ||
| Age (yrs) | 57.8 ± 10.7 | 54.6 ± 9.2 | 64,2 ±10.1 | F = 7.0 ** | = 0.002 |
| Gender (male) | 14 | 21 | 21 | χ 2 = 5.3 * | =0.071 |
| At disease onset | - | 44.5 ± 8.7 | 52.5 ± 9.6 | t = 3.1 | =0.03 |
|
| |||||
| Disease duration (yrs) | - | 10.1 ± 5.5 | 11.7 ± 7.2 | t = 0.88 | =0.39 |
| Education (yrs) | 13.2 ± 2.9 | 13.4 ± 3.0 | 14.7 ± 3.6 | F = 1.7 ** | =0.18 |
|
| |||||
| LEU dose(mg/day) | - | 832 ± 425 | 821 ± 400 | t = 0.1 | =0.9 |
| DA (patients) | - | 14 | 16 | χ 2 = 1.4 | =0.27 |
| Antidepressants (patients) |
- | 4 | 2 | χ 2 = 0.45 | =0.4 |
|
| |||||
| UPDRS on | - | 15.5 ± 8.3 | 14.4 ± 5.8 | t = 0.5 | =0.6 |
| UPDRS off | - | 27.3 ± 9.1 | 26.8 ± 6.7 | t = 0.2 | =0.8 |
| Improvement in UPRDS (%) |
- | 43.2 | 46.2 | ||
|
| |||||
| Gambling | - | 11 | - | ||
| Hypersexuality | - | 13 | - | ||
| Shopping | - | 8 | - | ||
| Punding | - | 4 | - | ||
| Kleptomania | - | 1 | - | ||
UPDRS = Unified Parkinson’s Disease Rating Scale; LEU = L-dopa equivalent units; DA = dopamine agonists. All values are mean ± SD.
*
= Chi-square
**
= F value.