Fig. 4.

Labeling and, hence, chemical knock-down of specific proteasome active sites. HEK293T lysates (10 μg total protein) were incubated with the indicated concentrations of probes for 1 h at 37 °C. Merged image of fluorescence scanned at λ_ex 488, λ_em 520 nm in green and λ_ex 532, λ_em 560 nm in red.