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Patterns of Viral Response as Predictors of Sustained Viral Response in Children with Genotype 1 treated with Peginterferon plus Ribavirin or Peginterferon plus Placebo
| Response | % Achieving Response | % With Response Achieving SVR | PPV | NPV |
|---|---|---|---|---|
| 1 log drop - Week 1 | 64% | 37% | 0.37 | 0.63 |
| RVR (no detectable virus) - Week 5 | 9% | 100% | 1.00 | 0.75 |
| EVR (2 log drop) - Week 12 | 55% | 56% | 0.56 | 0.89 |
Notes: PPV = probability of SVR given earlier response NPV = probability of no SVR given no earlier response
