Table 1.
Subtype | Median Age, y (Range) |
Median Preoperative Serum CA125, U/mL (Range) |
Stage | N | Nectin 4 Positive |
Silverberg Grade |
N | Nectin 4 Positive |
Nectin 4 Positive Overall |
---|---|---|---|---|---|---|---|---|---|
Serous (n = 212) | 59.6 (33.5–86.0) | 108 (0–23,000) | I | 50 | 29 (58) | 1 | 12 | 4 (33) | 107 (50.5) |
II | 93 | 47 (51) | 2 | 56 | 30 (54) | ||||
III | 69 | 31 (45) | 3 | 144 | 73 (50.7) | ||||
Endometrioid (n = 125) | 54.1 (29.4–88.1) | 130 (8–13,000) | I | 69 | 40 (58) | 1 | 82 | 49 (60) | 72 (57.6) |
II | 50 | 29 (58) | 2 | 35 | 19 (54) | ||||
III | 6 | 3 (50) | 3 | 8 | 4 (50) | ||||
Clear cell (n = 132) | 55.0 (28.1–89.0) | 64 (4–7,750) | I | 68 | 34 (50) | 1 | 0† | 0 (0) | 55 (41.7) |
II | 56 | 17 (30) | 2 | 0† | 0 (0) | ||||
III | 8 | 4 (50) | 3 | 132 | 55 (41.7) | ||||
Mucinous (n = 31) | 56.4 (25.4–76.7) | 45 (7–650) | I | 18 | 6 (33) | 1 | 11 | 2 (18) | 9 (29) |
II | 12 | 2 (17) | 2 | 18 | 6 (33) | ||||
III | 1 | 1 (100) | 3 | 2 | 1 (50) | ||||
Total (n = 500) | 56.6 (25.4–89.0) | 98 (0–23,000) | I | 205 | 109 (53.2) | 1 | 105 | 55 (52.4) | 243 (48.6) |
II | 211 | 95 (45.0) | 2 | 109 | 55 (50.5) | ||||
III | 84 | 39 (46) | 3 | 286 | 133 (46.5) |
Data are given as number (percentage) unless otherwise indicated.
All clear cell carcinomas are considered high grade.