Skip to main content
. 2011 Feb;162(4):890–896. doi: 10.1111/j.1476-5381.2010.01092.x

Figure 4.

Figure 4

Effects of isoprenaline (ISO) on slow delayed rectifier K+ (IKs) current. (A–C) IKs tail current traces obtained at repolarization to −40 mV under control conditions (A), following exposure to 100 nM ISO (B) and after washing the cells in ISO-free solution (C). (D) Representative experiment demonstrating the effect of 100 nM ISO on IKs and the full suppression of the ISO-induced current by 1 µM HMR-1556. (E) Average data obtained in 11 myocytes showing the cumulative effect of 10 nM and 100 nM ISO on IKs tail current amplitude. Columns and bars are means ± SEM values. *Indicates significant (P < 0.05) differences from control determined using paired t-test.