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. Author manuscript; available in PMC: 2011 Feb 21.
Published in final edited form as: Oncogene. 2010 May 31;29(30):4261–4275. doi: 10.1038/onc.2010.197

Figure 2. 15-LOX2 or 15-LOXsv-b expression results in enlargement of mouse prostates.

Figure 2

(A) Graph showing wet VP weights (mg; right) or ln (weight) of wt (n = 91), fl26 (n = 68) and svb9 (n = 91) mice as a function of animal age.

(B) Representative images (>5 for each genotype) of microdissected VP lobes of 2.5 month-old wt, fl26, svb9 mice showing increased prostate size in transgenic mice (scale bar = 1 mm).

(C) Branching morphogenesis of representative VP lobes (4 for each genotype) microdissected from wt and transgenic mice depicting the differences in the length of branches and the complexity of branching pattern.

(D) Branch lengths of the microdissected VPs from old (25 – 30 months) wt or transgenic animals (n = 5 per genotype). *P<0.05.