Table 3.
Association between clinical parameters and bone formation (osteocalcin) and bone resorption (TRAP, NTx)
| Osteocalcin |
TRAP |
NTx |
||||
|---|---|---|---|---|---|---|
| Parameter | R | P-value | R | P-value | R | P-value |
| Age, years | −0.37 | <0.0001 | −0.42 | <0.0001 | −0.66 | <0.0001 |
| Gender | – | 0.01 | – | 0.44 | – | 0.058 |
| Ethnicity | – | 0.52 | – | 0.31 | – | 0.90 |
| Height, cm | −0.07 | 0.37 | −0.18 | 0.02 | −0.26 | 0.002 |
| Weight, kg | −0.23 | 0.004 | −0.27 | 0.0006 | −0.32 | 0.0001 |
| SLEDAI, units | −0.29 | 0.0002 | −0.23 | 0.004 | −0.09 | 0.26 |
| Prednisone, mg/kg/day | −0.34 | <0.0001 | −0.04 | 0.67 | −0.04 | 0.64 |
| 25-OH-vitamin D, ng/ml | 0.15 | 0.07 | 0.15 | 0.07 | −0.05 | 0.58 |
| 1,25-OH2-vitamin D, ng/ml | 0.21 | 0.009 | 0.06 | 0.50 | 0.20 | 0.015 |
| PTH, ng/l | 0.02 | 0.79 | 0.003 | 0.97 | −0.01 | 0.87 |
| Osteocalcin, ng/ml | – | – | 0.36 | <0.0001 | 0.67 | <0.0001 |
| TRAP, U/l | 0.36 | <0.0001 | – | – | 0.41 | <0.0001 |
| NTxa | 0.03 | <0.0001 | 0.41 | <0.0001 | – | – |
R-values are reported for continuous variables. anM BCE/mM creatinine; n = 166 for osteocalcin; n = 157 for TRAP; n = 153 for NTx. P > 0.10.