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. 2011 Feb 1;11:4. doi: 10.1186/1472-6793-11-4

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Copyright ©2011 Yamazaki et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Summary whole-cell patch clamp currents and reversal voltage with only Na⁺or Li⁺as the major permeant ions. A) Bar graph of the reversal voltage (left panel), the currents at -100 mV (middle panel) and the conductance at -100 mV (right panel) in Na⁺-rich symmetrical solutions (B2, P2) and Li⁺-rich bath and Na⁺-rich pipette solutions (B4, P2). Data were taken from the rapid transition between Na⁺-rich and Li⁺-rich bath (time points 3 and 4' in Fig 3A) in order to minimize the contribution of rundown. B) Summary of current-voltage (I-V) relationships of the whole cell currents in symmetrical Na⁺-rich solutions (B2, P2) and Li⁺-rich bath and Na⁺-rich pipette solutions (B4, P2) at steady state (near 200 ms).