Table 1.
MCI (n=19) | NIE (n=19) | Sig. level | |
---|---|---|---|
Age, y, (SD) | 73 (9) | 75 (6) | .39 |
Male, (%) | 13 (68) | 6 (32) | .02* |
Body Mass Index | 27 (3) | 26 (5) | .48 |
Physical Activity Scale in Elderly | 155 (70) | 125 (47) | .15 |
Blood pressure, Systolic | 121 (16) | 126 (15) | .31 |
Blood pressure, Diastolic | 63 (11) | 63 (8) | 1.0 |
APOE-ε4 carrier, (%) | 8 (42) | 5 (26) | .32 |
Albumin, serum, g/dL | 4.0 (0.3) | 3.9 (0.3) | .18 |
Creatinine, serum, g/dL | 1.0 (0.2) | 1.0 (0.2) | .50 |
Homocysteine, plasma, μmol/L | 8.6 (2.5) | 8.6 (2.5) | .96 |
Cholesterol, plasma, mg/dL | 188 (32) | 201 (32) | .05 |
Calories consumed, total kCal | 1549 (566) | 1679 (505) | .46 |
Mini Mental State Exam | 26 (2.0) | 29 (1.0) | <.001* |
Neurobehavioral Cognitive Status Exam, Total | 69 (5) | 77 (2) | <.001* |
Clinical Dementia Rating | .35 (0.2) | .0 (0.0) | <.001* |
WMS-R, Delayed Paragraph Recall | 5 (6) | 12 (5) | .01* |
Geriatric Depression Scale | 2 (1) | 1 (2) | .54 |
Hachinski Ischemia Score | 1 (1) | 1 (0) | .08 |
Acetylcholine esterase inhibitor use, (%) | 74 | 0 | <.001* |
Statin use, (%) | 63 | 11 | <.001* |
Multivitamin use, (%) | 58 | 68 | .51 |
MCI, amnestic – Mild Cognitive Impairment; NIE, Non-impaired elders
Mean and SD unless labeled otherwise,
Significance level set at P ≤ .05
Multivitamin use derived by interview with subject (and collateral historian for MCI), including examination of all bottles from which subject was regularly taking pills; WMS-R, Wechsler Memory Scale – Revised