Table 1.
Characteristics of patients with COPD
| Parameter | COPD patients (n=60) |
|---|---|
| Age, years | 62.5±10.1 |
| Sex, M/F | 55/5 |
| BMI, kg/m2 | 25.5±4.7 |
| Current smokers, n (%) | 22 (36.7) |
| Cigarettes, pack years | 32±17 |
| Hypertension, n (%) | 28 (46.7) |
| Diabetes, n (%) | 9 (15) |
| Previous MI, n (%) | 4 (6.7) |
| Spirometry | |
| FEV1, % predicted | 55.6±15.8 |
| FEV1/FVC, % predicted | 58.1±10.7 |
| VC, % predicted | 77.7±14.3 |
| Echocardiography | |
| EF, % | 61.4±8.6 |
| RVSP, mm Hg | 40.9±9.5 |
| Laboratory tests | |
| Glucose, mM | 4.7 (1.0) |
| Creatinine, µM | 86.5±20.2 |
| Fibrinogen, g/l | 4.14±1.60 |
| CRP, mg/l | 2.87 (5.16) |
| IL-6, pg/ml | 3.07 (3.32) |
| TNFα, pg/ml | 1.93 (0.85) |
| MMP-9, ng/ml | 482.8 (266.6) |
| F1.2, pM | 195.9 (80.9) |
Results are expressed as mean ± SD or median (interquartile range). BMI, body mass index; CRP, C-reactive protein; EF, ejection fraction of left ventricle; F1.2, prothrombin fragment 1.2; FEV, forced expiratory volume in 1 second; FVC, forced vital capacity; IL-6, interleukin 6; MMP-9, matrix metalloproteinase 9; RVSP, right ventricle systolic pressure; TNFα, tumor necrosis factor α; VC, vital capacity