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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Nanomedicine. 2010 Sep 23;7(2):201–209. doi: 10.1016/j.nano.2010.07.008

Figure 3.

Figure 3

Biodistribution of systemically administered LDP micelles, untargeted (A) and folate-targeted (B) in nude mice bearing KB xenografts (mean±SEM, n=3-5) over a 5 day period, measured in units of percentage injected dose/gram tissue (%ID/g). Slower cumulative clearance of the targeted micelle can be attributed to the sustained accumulation in KB tumors as well as the presence of FRs in the kidneys. (C) Targeted micelle imaged in the right flank KB tumor of nude mice 48 h post injection shows excellent tumor extravasation.