Figure 2.

Role of cofilin phosphorylation on OHC electromotility (A) and slow OHC motility (B). (Aa) Electromotile amplitude in control (n = 5) and Y27632-exposed (n = 5) OHCs. (Ab) Electromotile amplitude in S3 (n = 7) and S3RV-treated (n = 4) OHCs. Control values are the same that in panel Aa. (Ac) NLC measurements, corresponding to single, representative cells, showing no effects of treatment on Prestin performance. (Ba) Slow changes in total length in control (n = 10) and Y27632-exposed (n = 14) OHCs. (Bb) Slow length changes in OHCs exposed to S3 (n = 6) and S3RV (n = 5). Control values are the same that in panel Ba, and were included here for comparison. (Points and vertical bars represent mean ± SE.)