Table 2.
Marker metabolites found in normal and cancer groups
| Metabolites | Retention time | P value1 | A (normal) | B (cancer2) | R3 |
| Lactic acid | 7.196 | 2.4 × 10-5 | 79.24 ± 6.1 | 187.04 ± 71.99 | 1.36 |
| Butanoic acid | 9.412 | 0.000 | 16.79 ± 0.52 | 27.33 ± 4.98 | 0.63 |
| Propanoic acid | 14.293 | 0.000 | 60.58 ± 9.79 | 147.77 ± 15.3 | 1.43 |
| Glycerol | 12.511 | 0.000 | 147 ± 8.98 | 269.13 ± 50.31 | 0.83 |
| Pyrimidine | 14.705 | 0.000 | 61.68 ± 8.05 | 163.11 ± 12.23 | 1.64 |
| Butanedioic acid | 13.933 | 0.1 × 10-5 | 161.51 ± 5.85 | 267.89 ± 54.64 | 0.66 |
| Malic acid | 19.301 | 0.000 | 10.7 ± 1.91 | 32.15 ± 1.16 | 2.00 |
| Citric acid | 28.768 | 1.4 × 10-4 | 1291.89 ± 364.74 | 2164.74 ± 529.58 | 0.68 |
| Hexadecanoic acid | 34.612 | 4.17 × 10-4 | 1347.84 ± 304.67 | 2066.57 ± 437.28 | 0.53 |
| Uric acid | 35.691 | 0.000 | 172.2 ± 17.03 | 214.52 ± 7.74 | 0.25 |
1
P values were calculated based on Student t test (significance at P < 0.05);
2
Cancer group included the non-metastasis group and the metastasis group;
3
R value was calculated from the arithmetic mean values of each group. R = (B-A)/A. R with a positive value indicates a relatively higher concentration in cancer group while a negative value means a relatively lower concentration as compared with the normal group.