Table 3.
Metabolic differences in the two groups
| Metabolites | Retention time | P value1 | A (non-metastasis) | B (metastasis) | R2 |
| Alanine | 8.105 | 0.000 | 173.75 ± 39.59 | 19.28 ± 10.63 | -0.89 |
| Butanoic acid | 9.412 | 0.000 | 32.09 ± 1.00 | 22.58 ± 0.72 | -0.30 |
| Glycerol | 12.511 | 0.003 | 303.23 ± 26.16 | 235.04 ± 45.64 | -0.22 |
| Butanedioic acid | 13.933 | 0.1 × 10-5 | 216.36 ± 2.63 | 319.43 ± 17.89 | 0.48 |
| L-proline | 20.497 | 0.000 | 184.99 ± 10.26 | 117.78 ± 7.05 | -0.36 |
| L-threonic acid | 20.909 | 2.28 × 10-4 | 284.94 ± 46.47 | 181.48 ± 37.25 | -0.36 |
| Myo-inositol | 29.032 | 0.000 | 33.08 ± 3.58 | 114.8 ± 2.20 | 2.47 |
1
P values were calculated based on Student t test (significance at P < 0.05);
2
R value was calculated from the arithmetic mean values of each group. R = (B-A)/A. R with a positive value indicates a relatively higher concentration in metastasis group while a negative value means a relatively lower concentration as compared with the non-metastasis group.