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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Drug Discov Today Dis Models. 2010 SPRING;7(1-2):27–33. doi: 10.1016/j.ddmod.2010.11.001

Figure 3. Periodic Acid Schiff staining of rat PHN kidneys.

Figure 3

The GBM lining the outer aspect of the capillary loops is smooth and thin in rats administered control sheep serum at 1 month (A, 400× and 1000× magnification) and 6 months (C, 400× and 1000× magnification). The GBM lining the outer aspect of the capillary loops is thicker (B, 400× and 1000× magnification, arrow heads) and some podocytes have abnormal shape (B, thin arrow) in rats administered sheep-anti Fx1a (PHN) at 1 month. Following six months of PHN and ongoing proteinuria, some glomeruli have become sclerotic (D, 400× and 1000× magnification).