Table 1. Known homologs of human P-bodies components in Arabidopsis.
| Gene | AGI(AT) | Genetic alleles | Description of alleles | Yeast | Human |
|---|---|---|---|---|---|
| DECAPPING 1 | 1G08370 | dcp1-1;dcp1-2 | Post-embryonic lethal [8••,9•] | DCP1 | DCP1a DCP1b |
| DECAPPING 2 | 5G13570 | dcp2-1;dcp2-2; dcp2-3 | Post-embryonic lethal [8••,9•] | DCP2 | DCP2 |
| tdt1-1;tdt1-2(dcp2-1) | Vascular defects, post-embryonic lethal [12•] | ||||
| VARICOSE | 3G13300 | vcs-1; vcs-2; vcs-3;vcs-4;vcs-5 | Leaf blade and shoot apical meristem defects, temperature sensitive [19] | Hedls Ge-1 |
|
| vcs-6;vcs-7 | Post-embryonic lethal [8••] | ||||
| DECAPPING 5 | 1G26110 | dcp5-1 | Germination slow, abnormal vein development, defect in mRNA decapping, P-body formation and translational repression [11••] | SCD6 | RAP55 |
| EXORIBONUC LEASE 4 | 1G54490 | xrn4-1 | Elevated transgene silencing [20•] | XRN1 | XRN1 |
| xrn4-4;xrn4-5 | Over-accumulation of specific mRNAs including 3′ products of miRNA-mediated cleavage [21] | ||||
| ein5 | Ethylene insensitive, over-accumulation of EBF1 and EBF2 mRNAs [22,23] elevated small RNA processing [24] | ||||
| DExD/H-BOX HELICASE 1 | 3G61240 | dhh1-1* | DHH1 | Rck/p54 | |
| SUPERSENSITI VE TO ABA AND DROUGHT 1 | 5G48870 | sad1 | Dwarf and small, hypersensitive to ABA and drought [25] | LSM5 | hLSM5 |
| LIKE Sm 4 | 5g27720 | emb1644-1;emb1644-2 | Embryo defective from globular stage (http://www.seedgenes.org) | LSM4 | hLSM4 |
| ARGONAUTE 1 | 1G48410 | ago1-3 | Infertile, defect in gene silencing [26], including translation inhibition [27] | hAGO1 | |
| SILENCING DEFECTIVE 3 | 1G05460 | sde3-1;sde3-2 | Defect in transgene silencing [28] | MOV10 | |
| UP-FRAMESHIFT 1 | 5G47010 | upf1-3;lba1 | Seedling lethality [29,30•] | NAM7 | UPF1 |
| upf1-4;upf1-5 | Leaf and flower abnormality, defect in RNA interference [30•] | ||||
| UP-FRAMESHIFT 2 | 2G39260 | VIGS | Defect in degradation of aberrant spliced RNA [31,32••] | NMD2 | UPF2 |
| UP-FRAMESHIFT 3 | 1G33980 | upf3-1;upf3-2 | Leaf and flower abnormality [30], defect in degradation of aberrant spliced RNA [33] | UPF3 | UPF3 |
| SUPPRESSOR WITH MORPHOGENE TIC EFFECT ON GENITALIA 7 | 5G19400 | VIGS | Defect in degradation of aberrant spl.iced RNA [31,32••] | SMG-7 | |
| CCR4-ASSOCIATED FACTOR1a | 3G44260 | caf1a-1; caf1a-2 | Sensitive to abiotic and biotic stresses [34,35] | POP2 | CAF1 |
| CCR4-ASSOCIATED FACTOR1b | 5G22250 | caf1b-1; caf1b-2; caf1a/caf1 b | |||
| EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | 4G18040 | cum1-1;cum1-2 | Loss-of-susceptibility to potyviruses [36] | CDC33 | eIF4E |
| ISO-EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | 5G35620 | lsp1; ateIF(iso) 4E-1 | Loss-of-susceptibility to potyviruses [37,38] |
*
Xu and Chua, unpublished