Table 5.
Subjects With Amyloid-Associated Depression + Without Depression |
Subjects With Nonamyloid Depression + Without Depression |
|||||||
---|---|---|---|---|---|---|---|---|
LM Delayed Recall (n=735) |
Block Design (n=710) |
LM Delayed Recall (n=730) |
Block Design (n=704) |
|||||
β Estimate (SE) |
P Value |
β Estimate (SE) |
P Value |
β Estimate (SE) |
P Value |
β Estimate (SE) |
P Value |
|
Age, y | −0.3 (0.04) | <.001 | −0.2 (0.04) | <.001 | −0.3 (0.04) | <.001 | −0.2 (0.04) | <.001 |
School, y | 0.9 (0.1) | <.001 | 0.8 (0.1) | <.001 | 0.9 (0.1) | <.001 | 0.9 (0.1) | <.001 |
APOE4 | −1.5 (0.7) | .04 | −2.0 (0.7) | .005 | −1.1 (0.8) | .16 | −1.1 (0.7) | .14 |
Antidepressant use | 1.3 (0.8) | .09 | 0.1 (0.7) | .87 | 0.4 (0.8) | .65 | 0.5 (0.7) | .46 |
Amyloid-associated depression | −1.9 (0.4) | <.001 | −1.4 (0.4) | <.001 | ||||
Nonamyloid depression | −0.9 (0.8) | .30 | .30 | <.001 |
Abbreviation: LM, Logical Memory.
All of the listed variables were included in the regression model after adjusting for sex, race, creatinine level, diabetes mellitus, stroke, and cardiovascular disease. Because Bonferroni correction was applied, P<.0167 is considered significant.