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A, B) Examination of remodeling, extramyocyte space, and collagen location in the LV using hematoxylin (A) and Masson's trichrome staining (B) in young (6 mo) and old (34 mo) sedentary (YS, OS) and exercise-trained (YE, OE) FBNF1 rats. Unstained areas indicate extramyocyte space for hematoxylin staining (A); unstained areas are dark gray for Masson's trichrome imaging (B). C) Percentage collagen area. aP < 0.05 vs. YS; bP < 0.05 vs. YE; cP < 0.05 vs. OS.
