Fig. 3.
Khc IAK motif mutations inhibit body axis patterning in oocytes. (A) Fluorescent in situ hybridization images for osk mRNA in wild-type (left) and Khc77 mutant (right) Drosophila oocytes at the indicated stages of oogenesis. The arrow indicates a lagging central concentration of osk in stage-9 mutants. Scale bars: 25 μm in stage 8; 50 μm in stages 9 and 10A. (B) Eggs from female germline clones homozygous for the Khc alleles indicated on the left were scored for defects in dorsal appendage morphology that indicate defective dorsal-ventral patterning.