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. 2011 Mar 15;138(6):1161–1172. doi: 10.1242/dev.057620

Fig. 2.

Fig. 2.

Normal differentiation of E15 Fz4−/−;Fz8−/− kidneys as determined with molecular markers. (A-L) In situ hybridization for the indicated transcripts shows a normal density and arrangement of nephron progenitors (Six2), podocytes (i.e. glomeruli; Podx1), the thick ascending limb of the loop of Henle and early distal convoluted tubules (uromodulin), proximal convoluted tubules (Slc34a1), pretubular aggregates (Wnt4) and distal convoluted tubules (Slc12a3) in Fz4−/−;Fz8−/− versus Fz4+/+;Fz8−/− mouse kidneys at E15. Scale bar: 400 μm.