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. 2011 Feb 1;9:18. doi: 10.1186/1477-7827-9-18

Table 3.

Effect of BMP4 and Noggin added to in vitro maturation medium on development of parthenogenic and in vitro fertilized embryos

Treatment Total Cleaved (%) Blastocysts (%) Hatching blast. (%) Blastocyst cell number ± sd
Control 344 190 (55.2)b 30 (8.7) 100 ± 33
PA BMP4 274 180 (65.7)a 22 (8.0) 1(0.4) 88 ± 14
Noggin 242 158 (65.3)a 22 (9.0) 68 ± 8
Control 249 176 (70.7)α 35 (14.0) 5 (2.0) 90 ± 25
IVF BMP4 221 160 (72.4)α 28 (12.6) 4 (1.8) 120 ± 25
Noggin 234 144 (61.5)β 31(13.2) 2 (0.8) 99 ± 8

Development of parthenogenic (PA) and in vitro fertilized (IVF) embryos produced from oocytes that were matured in the presence of 100 ng/ml of BMP4 or Noggin. Controls were matured in standard medium without supplementation. Different superscripts in PA or IVF indicate statistical differences (Chi-square test, p < 0.05). For blastocyst cell numbers, one-way ANOVA was applied