Table 3.
Univariate Cox proportional hazard regression analysis in subsets of patients according to eGFR level
| Variables | All patients |
eGFR < 45 mL/min |
eGFR > 45 mL/min |
|||
|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| For renal progression | n = 35/268 | n = 31/164 | n = 4/104 | |||
| Serum total IS, mg/L | 1.063 (1.041–1.085) | < 0.001 | 1.051 (1.027–1.075) | < 0.001 | 0.553 (0.09–3.405) | 0.523 |
| Serum total PCS, mg/L | 1.092 (1.060–1.126) | < 0.001 | 1.074 (1.038–1.111) | < 0.001 | 1.049 (0.821–1.340) | 0.702 |
| For all-cause mortality | n = 14/164 | n = 11/164 | n = 3/104 | |||
| Serum total IS, mg/L | 1.014 (0.956–1.075) | 0.647 | 1 (0.934–1.071) | 0.993 | 0.248 (0.015–4.2) | 0.334 |
| Serum total PCS, mg/L | 1.099 (1.053–1.148) | < 0.001 | 1.104 (1.049–1.160) | < 0.001 | 0.883 (0.468–1.668) | 0.702 |
Abbreviation: PCS, p-cresyl sulphate; IS, indoxyl sulphate.