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. 2011 Feb 22;6(2):e16915. doi: 10.1371/journal.pone.0016915

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Enerly et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The panels show miRNAs that are both positively and negatively associated with proliferation in transfected cell-lines. (A) list of miRNAs that showed a significant effect on proliferation in cell-lines with a corresponding differential expression in tumors. (* indicates opposite effect in MCF-7 and BT-474). (B) Lysate microarray (LMA) screening of MCF-7 and BT-474 cells transfected with 20 nM human Pre-miR™ miRNA Precursor library v2. Ki67 readout after 48 and 72 hours. The two miRNAs from panel A with strongest positive and negative effect on proliferation for each cell line are shown (see Table S7 for complete list)