Skip to main content
. Author manuscript; available in PMC: 2012 Feb 24.
Published in final edited form as: Vaccine. 2011 Jan 15;29(10):1968–1973. doi: 10.1016/j.vaccine.2010.12.075

Figure 3.

Figure 3

Bactericidal activity against group B strain M4407. Panels A-D show data for subjects 1–4, respectively. Left panels, mean bactericidal titers of unadsorbed pre-immunization sera (horizontal hatched bars) and the respective post-immunization sera: unadsorbed (bars with diagonal hatching), adsorbed two times with the negative control rHA-coupled immunoadsorbent (open bars) and adsorbed with both anti-NHba and anti-fHbp antibodies (green bars). The error bars represent the respective ranges of values measured in two to three independent assays. On some bars, the ranges are not evident because the respective ranges were small. Right panels, percent survival after incubation of the test strain for 60 minutes with human complement and dilutions of post-immunization test sera before (X with solid line) or after depletion of antibodies to fHbp (yellow circles, dashed lines), NHba (blue circles, solid lines), or recombinant human albumin (negative control, open triangles, dashed lines). Data shown are from a representative experiment, which were confirmed in at least two or three independent experiments.