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. 2011 Mar 2;100(5):1178–1188. doi: 10.1016/j.bpj.2011.01.041

Table 3.

Number of binding sites estimated by Prony's method

M1 M2 M3
No noise 1S 0% 0% 0%
2S 100% 100% 0%
3S 0% 0% 100%
>3S 0% 0% 0%
With noise 1S 2% 14% 0%
2S 87% 84% 56%
3S 11% 2% 44%
>3S 0% 0% 0%

A data set without noise and 100 noisy data sets (n ∼ N (0.00, 0.03)) with different underlying model types (M1, reaction-dominant (2S); M2, full reaction-diffusion with single diffusion (2S); and M3, full reaction-diffusion with multiple diffusion (2S)) were analyzed by Prony's method. Entries in bold highlight the most likely number of binding sites S.