Table 3.
Number of binding sites estimated by Prony's method
M1 | M2 | M3 | ||
---|---|---|---|---|
No noise | 1S | 0% | 0% | 0% |
2S | 100% | 100% | 0% | |
3S | 0% | 0% | 100% | |
>3S | 0% | 0% | 0% | |
With noise | 1S | 2% | 14% | 0% |
2S | 87% | 84% | 56% | |
3S | 11% | 2% | 44% | |
>3S | 0% | 0% | 0% |
A data set without noise and 100 noisy data sets (n ∼ N (0.00, 0.03)) with different underlying model types (M1, reaction-dominant (2S); M2, full reaction-diffusion with single diffusion (2S); and M3, full reaction-diffusion with multiple diffusion (2S)) were analyzed by Prony's method. Entries in bold highlight the most likely number of binding sites S.