Table 2.
Urine concentration of KIM-1 and NGAL in patients with UPJO (study group and control 1) and healthy controls (control 2).
| Exama/group | uKIM-1 (ng/ml) | uKIM/cr. (ng/mg cr.) | uNGAL (ng/ml) | uNGAL/cr. (ng/mg cr.) |
|---|---|---|---|---|
| Exam A (voided urine before pyeloplasty) | 1.35 A, b (0.96–6.76) | 3.13 A, b (0.6–10.73) | 8.38 A, b (3.3–55.22) | 23.66 A, b (2.04–60.35) |
| Exam B (urine samples from affected pelvis during surgery) | 1.37 b (0.27–5.3) | 3.42 B, b (0.19–9.59) | 12.43 A, b (1.78–100.0) | 38.48 B, b (1.5–131.23) |
| Exam C (voided urine 3 months after surgery) | 1.41 b (0.6–4.88) | 1.73 A, b (0.48–6.94) | 3.37 b (1.09–55.3) | 5.62 a (2.15–25.78) |
| Control 1 (children had suspected but not confirmed UPJO) | 0.84 b (0.23–2.71) | 1.04 (0.18–5.69) | 3.94 b (1.23–12.15) | 3.8 a (0.9–44.77) |
| Control 2 (healthy children) | 0.37 (0.15–1.82) | 0.58 (0.15–3.01) | 1.64 (0.25–5.77) | 2.31 (0.27–16.27) |
uKIM-1, Urinary kidney injury molecule-1; uNGAL, urinary neutrophil gelatinase-associated lipocalin; cr., creatinine; UPJO, ureteropelvic junction obstruction
Values are given as the median with the range given in parenthesis
p A < 0.05 to control 1, p a < 0.05 to control 2; p B < 0.01 to control 1, p b < 0.01 to control 2