Table 6.
Associations between environmental exposures and SEB-induced IL-10. Model 1 was adjusted for age, sex, and maternal educational level. Model 2 was adjusted for age, sex, maternal educational level and other covariates excluding residence. Shown are Fold change (FC) and 95% confidence intervals (95% CI). Environmental exposures with significant effects (P < 0.01) are shown in bold. Univar.—univariate analyses; Primary—completed primary education.
| Exposure/factor | Analysis | SEB-induced IL-10 |
||
|---|---|---|---|---|
| FC | 95% CI | P value | ||
| Age | Univar. | 0.50 | 0.33–0.76 | 0.001 |
| Sex | Univar. | 1.83 | 0.02–3.66 | 0.09 |
| Maternal education (Illiterate vs. primary) | Univar. | 0.86 | 0.36–2.10 | 0.75 |
| Residence (urban vs. rural) | Univar. | 8.56 | 4.61–15.91 | < 0.001 |
| Crowding | Model 1 | 1.26 | 1.06–1.51 | 0.01 |
| Model 2 | 1.35 | 1.12–1.62 | 0.002 | |
| Piped water | Model 1 | 0.32 | 0.15–0.68 | 0.003 |
| (yes vs. no) | Model 2 | 0.37 | 0.17–0.84 | 0.02 |
| Birth order | Model 1 | 1.08 | 0.55–2.13 | 0.83 |
| (≥ 3 rd vs. 1st/2nd) | Model 2 | 0.83 | 0.39–1.73 | 0.61 |
| Breast-feeding | Model 1 | 0.80 | 0.35–1.74 | 0.54 |
| (≥ 13 months vs. ≤ 12 months) | Model 2 | 0.70 | 0.31–1.57 | 0.39 |
| Bathroom | Model 1 | 0.41 | 0.16–1.06 | 0.07 |
| (field vs. other) | Model 2 | 0.52 | 0.19–1.41 | 0.20 |
| House construction | Model 1 | 1.05 | 0.47–2.33 | 0.91 |
| (cement vs. wood) | Model 2 | 0.21 | 0.52–2.82 | 0.65 |
| Geohelminth infection | Model 1 | 0.50 | 0.23–1.08 | 0.08 |
| (yes vs. no) | Model 2 | 0.49 | 0.24–1.07 | 0.07 |