Table 1.
Evaluation of presence of cells making the different cytokines in the same tissue section.
Therapeutic response (r2) | ||
---|---|---|
Cytokines | Good | Poor |
IFN-γ× TGF-β | 0·2053 | 0·8774 |
IFN-γ× IL-10 | 0·2395 | 0·5591 |
IL-10 × TGF-β | 0·5836 | 0·7111 |
Using linear regression analysis, we found a linear relationship between the numbers of cells expressing two cytokines in the same tissue section. Considering response to therapy, we could observe a strong correlation (high r2) of cells expressing transforming growth factor (TGF)-β and interleukin (IL)-10 or interferon (IFN)-γ in lesions from poor responder patients. The values are expressed in r2.