Fig. 5.

Histological examination of middle ears of wild-type mice (a) (b), chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)^–/– mice (c), D prostanoid receptor (DP)^–/– mice (d) or DP^–/– CRTH2^–/– mice (e). Wild-type mice received lipopolysaccharide (LPS) (a) or phosphate-buffered saline (PBS) (b). Mutant mice were injected with LPS (c–e). Middle ear tissues were stained with haematoxylin and eosin.