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. Author manuscript; available in PMC: 2012 Jan 7.
Published in final edited form as: Cell Stem Cell. 2011 Jan 7;8(1):106–118. doi: 10.1016/j.stem.2010.12.003

Figure 5.

Figure 5

Duplications on chromosome 20 arising over a five day period during directed differentiation of hESCs to cardiomyocytes. (A) The top two panels show the BAF and LRR plots at Day 2 of the differentiation protocol; the bottom two panels show the plots at Day 7. Three segments showing different degrees of separation of the “cloud” of BAF values for heterozygous SNPs are labeled 1, 2, and 3. (B) The BAF distance for heterozygous SNPs are shown for regions duplicated on chromosome 20. The BAF distance for mixtures of known ratios of HDF51 cells (which have no duplication on chromosome 20) and HDF51IPS11P33 cells (which have a duplication of the proximal portion of the q-arm) are shown on the left (BAF and LRR plots are shown in Figure S4A). The BAF distances for the three partially duplicated segments (corresponding to the segments labeled 1, 2, and 3 in A) are shown on the right, and have been used to estimate the percent of the population carrying the duplication. See also Figure S5.