Skip to main content
. Author manuscript; available in PMC: 2011 Feb 23.
Published in final edited form as: J Med Genet. 2010 Aug 15;47(11):745–751. doi: 10.1136/jmg.2009.076703

Figure 6.

Figure 6

A cartoon illustrating various categories of subtelomeric 4q and 10q genotypes (I–VII; large white rectangles) analysed by Southern blotting after digestion with EcoRI, EcoRI plus BlnI and XapI (ApoI) and probing with p13E-11 (large yellow rectangles) or D4Z4 (single large light-green rectangle). Non-standard D4Z4 arrays on 4q that contain BlnIS units (black-filled boxes) and those on 10q that contain BlnIR units (white boxes) complicate the determination of whether a short array is present on 4q. These types of D4Z4 arrays with repeat units from chr10 on 4q are almost always mixed with canonical chr4-type units in various patterns, and those from chr4 on 10q are usually homogeneously chr4-type,11 34 as illustrated for categories IV–VII. Other combinations of translocated arrays are possible.35