DNV-induced changes in phosphorylation of mTOR (A) and p70S6K (B), as detected by Western analyses. A, top: representative immunoblot of phospho-mTOR, mTOR, and β-tubulin for each DNV time point. Bottom: relative expression (means ± SE) of phospho-mTOR, mTOR, and the ratio of phospho-mTOR to total mTOR, compared with sham control after normalization to β-tubulin. *Significantly different (P < 0.05; n = 5) from the average of all sham controls. B, top: representative immunoblot of phospho-p70S6K, p70S6K, and β-tubulin for each DNV time point. Bottom: relative expression (means ± SE) of phospho-p70S6K and p70S6K, compared with sham control after normalization to β-tubulin. *Significantly different (P < 0.05; n = 4) from the average of all sham controls.