Fig. 8.

DNV-induced changes in FoxO1 protein expression in cytoplasmic and nuclear cell fractions, as detected by Western analyses. Top: representative immunoblot of cytoplasmic and nuclear FoxO1 in sham control and at 1, 3, and 5 days after DNV. Bottom: relative expression (means ± SE) of cytoplasmic FoxO1 (left) and nuclear FoxO1 protein expression (right), each compared with sham control for the same cell fraction after normalization to β-tubulin. *Significantly different (P < 0.05; n = 3) from the sham control.