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. Author manuscript; available in PMC: 2011 Feb 23.
Published in final edited form as: Ann Thorac Surg. 2010 Dec;90(6):2001–2008. doi: 10.1016/j.athoracsur.2010.06.118

Table 4.

Histologic Damage Scores by Brain Region for 25°C LF and HCA Bypass Conditions

Brain Region 25°C, LF 25°C, HCA p Value
Cortex 0 (0 – 0) 2 (0 – 10)   0.03*
Caudate Nucleus 0 (0 – 0) 3 (1 – 4) <0.001*
Hippocampus 0 (0 – 0) 0 (0 – 1) 0.44
Thalamus 0 (0 – 0) 0 (0 – 0) 0.99
Cerebellum 1 (0 – 2) 2 (1 – 4)   0.02*
Total Sum 1 (0 – 2) 9 (4 – 19) <0.001*

Data are median scores with ranges shown in parentheses; n = 8 animals per group.

*

Statistically significant. p values are based on the Mann-Whitney U-test since histologic scores do not follow a normal distribution. LF = low flow; HCA = hypothermic circulatory arrest.