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. 2010 Dec 20;20(6):1049–1060. doi: 10.1093/hmg/ddq548

Figure 5.

Figure 5.

The PPAR pathway. Schematic depiction of the PPAR pathway with those genes highlighted that are selectively altered in their expression in DE5 transgenic mice. Red indicates an up-regulation of gene expression; green, a down-regulation. PPARα (Ppargc1a), peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Coup-tf (Nr2f1), nuclear receptor subfamily 2, group F, member 1; Rxra (Rxra), retinoid X receptor alpha; Ncor1 (Ncor1), nuclear receptor co-repressor 1; Mras (Mras), muscle and microspikes RAS; Pdgfa (Pdgfa), platelet derived growth factor, alpha; TAB1 (Map3k7ip1), TGF-beta-activated kinase 1/MAP3K7 binding protein 1; Nfkbia (Nfkbia), nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha. Pathway depiction reproduced with permission from Ingenuity Systems Analysis (© 2000–2011 Ingenuity Systems, Inc. All rights reserved).