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The GABAAR antagonist bicuculline inhibits neuronal responses to EtOH. Spontaneous activity of VRC neurons before bicuculline and during bicuculline (blue line) and EtOH coapplication (blue and red lines). Individual units are normalized to the last 30 min of bicuculline treatment (before the application of EtOH). Corresponding VRC neuronal activity during 0.1 M EtOH application (from Fig. 6) is overlaid for comparison (gray trace). *P < 0.05, different than EtOH treatment.
